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Enterocutaneous Fistula - Surgical Lecture
PptxGenJS Presentation
Prof. Zahid Mahmood
Prof. Zahid Mahmood
1
2026-04-05T16:04:48Z
2026-04-05T16:04:48Z
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Enterocutaneous FistulaA Comprehensive Surgical LectureProf. Zahid MahmoodDepartment of SurgeryFinal Year MBBS | UHS / CPSP Aligned CurriculumBailey & Love Style · Exam-Oriented · Viva Ready · Case-Based LearningPK
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02Learning Outcomesâ–¶ Define enterocutaneous fistula; classify by output and anatomical siteâ–¶ Enumerate causes; understand pathophysiology and factors preventing healingâ–¶ Recognise clinical features; select appropriate investigations systematicallyâ–¶ Plan conservative and surgical management; list complications and prognosisProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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03Definition▶ Abnormal communication between gut lumen and skin surface — ECF▶ Accounts for 75–85% of all gastrointestinal fistulae (Bailey & Love)▶ Output defines severity: Low <200 ml/day, Moderate 200–500, High >500 ml/day▶ High-output ECF carries greatest risk: dehydration, malnutrition, sepsisProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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04Classification▶ By Output: Low (<200 ml/day), Moderate (200–500), High (>500 ml/day)▶ By Anatomy: Simple (short, direct tract), Complex (multi-track, abscess, radiation)▶ By Aetiology: Spontaneous (Crohn's, TB, malignancy) vs Iatrogenic (post-operative)▶ By Location: Duodenal, jejunal, ileal, colonic — determines management complexityProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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05Types / Variants — Clinical Relevance▶ External ECF: Bowel → skin; most common; visible fistula opening on abdominal wall▶ Entero-enteric: Bowel loop to bowel loop; bypass, diarrhoea, malabsorption▶ Entero-vesical: Bowel to bladder; pneumaturia, faecaluria — diagnostic hallmark▶ Entero-vaginal: Bowel to vagina; faecal discharge per vaginum; Crohn's / radiotherapyProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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06Etiology / Causes — FRIEND Mnemonic▶ F — Foreign body (mesh, suture); R — Radiation enteritis (delayed effect, ischaemic)▶ I — Inflammation/Infection (Crohn's disease, TB, actinomycosis, diverticulitis)▶ E — Epithelialisation of tract; N — Neoplasm (primary or secondary bowel tumour)▶ D — Distal obstruction; also: Iatrogenic (75–85% post-operative anastomotic leak)Prof. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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07Pathophysiology — Why Fistulae Persist▶ Anastomotic breakdown / bowel injury → bowel content leaks into wound/cavity▶ Tract epithelialises → permanent channel forms; spontaneous closure prevented▶ FRIEND factors maintain fistula: distal obstruction, foreign body, malignancy▶ High output → fluid/electrolyte loss → malnutrition → immunosuppression → sepsisProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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08Clinical Features — Signs & Symptoms▶ Wound discharge: enteric content through skin — characteristic presentation▶ Systemic: fever, tachycardia, weight loss, malnutrition — signs of sepsis/catabolism▶ Skin excoriation around fistula opening — from digestive enzymes (esp. proximal ECF)▶ High output: dehydration, hyponatraemia, hypokalaemia, metabolic acidosisProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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09Investigations — Labs & Imaging▶ Labs: FBC, U&E, LFTs, albumin (<25 g/L = severe malnutrition), CRP, fistula output pH▶ Fistulogram: Water-soluble contrast injected into tract — defines anatomy and course▶ CT Abdomen + Pelvis: Identifies abscess, distal obstruction, foreign body, malignancy▶ MRI / Barium studies: Delineate complex tracts; assess bowel continuity and diseaseProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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10Management Overview — SNAP Framework▶ S — Sepsis control: drain abscess, IV antibiotics, source control — FIRST priority▶ N — Nutrition: TPN or enteral feeding; restore positive nitrogen balance (albumin >30)▶ A — Anatomy: Delineate with fistulogram/CT; identify factors preventing closure▶ P — Plan: Wait 4–6 weeks for spontaneous closure; surgery if FRIEND presentProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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11Conservative Management▶ NBM + TPN: Bowel rest; high-output ECF requires parenteral nutrition support▶ Skin care: Stoma bag, barrier creams — protect peri-fistula skin from enzymes▶ Octreotide: Reduces GI secretions; aids closure of high-output fistulae▶ Spontaneous closure: 30–40% close within 4–6 weeks if no FRIEND factor presentProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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12Surgical Management▶ Timing: Delay 3–6 months — allow inflammation to settle, optimise nutrition (albumin >30)▶ Resection + primary anastomosis: Gold standard; excise fistula tract and diseased bowel▶ Bypass procedure: Proximal stoma; defunctioning if resection high-risk or anatomy complex▶ VSD / NPWT: Negative pressure wound therapy — controls output; aids wound healingProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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13Complications — Early & Late▶ Fluid/electrolyte: Severe dehydration, hyponatraemia, hypokalaemia — life-threatening▶ Sepsis: Intra-abdominal abscess, wound infection, bacteraemia → multi-organ failure▶ Malnutrition: Negative nitrogen balance, hypoalbuminaemia → impaired wound healing▶ Late: Persistent/recurrent fistula, skin ulceration, psychological morbidity, mortality 5–20%Prof. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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14Mnemonics & High-Yield Exam Points▶ FRIEND (causes): Foreign body · Radiation · Inflammation · Epithelialisation · Neoplasm · Distal obstruction▶ SNAP (management): Sepsis · Nutrition · Anatomy · Plan/Procedure — sequence is mandatory▶ VIVA POINT: Albumin <25 g/L = severe malnutrition; target >30 g/L before surgery▶ Spontaneous closure unlikely if: high output, short tract, distal obstruction, malignancy, radiationProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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Clinical Scenario — Case-Based LearningCASE: A 55-year-old male, 10 days post-elective right hemicolectomy for Crohn's disease, presents with enteric content discharging from a midline wound. Output is 650 ml/day. He is pyrexial (38.4°C), tachycardic, and has lost 4 kg since surgery. Albumin = 20 g/L. CT abdomen shows anastomotic dehiscence with a peri-anastomotic collection.Q1: What is the diagnosis and classification?✔ High-output ECF (>500 ml/day); post-operative (iatrogenic); complex typeQ2: What is the immediate management priority?✔ SNAP: Drain abscess → TPN → Fistulogram → Plan surgery after 3–6 monthsProf. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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MCQs — SBA Style (CPSP / UHS Pattern)1Q1. Commonest cause of enterocutaneous fistula?A) Crohn's disease B) Radiation C) Post-operative (iatrogenic) ✔ D) Malignancy2Q2. High-output ECF is defined as output greater than?A) 100 ml/day B) 200 ml/day C) 500 ml/day ✔ D) 1000 ml/day3Q3. First priority in management of ECF using the SNAP approach?A) Nutrition B) Surgery C) Sepsis control ✔ D) Anatomy definition4Q4. Which letter in FRIEND mnemonic causes ECF by mechanical interference?A) R (Radiation) B) F (Foreign body) ✔ C) I (Inflammation) D) N (Neoplasm)Prof. Zahid Mahmood | Enterocutaneous Fistula | Final Year MBBS | UHS / CPSP CurriculumPK
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High-Yield Summary 1ECF = abnormal bowel-to-skin communication; 75–85% are iatrogenic (post-operative) 2FRIEND causes prevent spontaneous closure — identify and correct before surgery 3SNAP sequence is mandatory: Sepsis → Nutrition → Anatomy → Plan/Procedure 4Surgery delayed 3–6 months; albumin must be >30 g/L; mortality remains 5–20%Prof. Zahid Mahmood | Enterocutaneous Fistula | End of LecturePK
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